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eLife

The Locomoting State Selectively Amplifies Activity of Sensitizing Neurons in Primary Visual Cortex

This manuscript presents a valuable analysis of how locomotion modulates the activity of different subtypes of cortical neurons in the mouse primary visual cortex, showing that locomotion more ...
Beirut Time

Mapping convergent regulators of melanoma drug resistance by PerturbFate

A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...
eLife

Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...